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  • Title: Surfactant in the amniotic fluid and bromhexine metabolite VIII.
    Author: Merkus JM, Roozen PH, Verhoeven AG, Kock HC.
    Journal: Eur J Obstet Gynecol Reprod Biol; 1978 Apr; 8(2):99-102. PubMed ID: 400861.
    Abstract:
    The effect of metabolite VIII of bromhexine on surfactant content in the amniotic fluid was investigated in a double blind study. Administration of 100 and 200 mg NA-872 daily for 5 days to pregnant women ranging in gestational age from 196 to 243 days was not followed by a significant rise in the L/S ratio.
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