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  • Title: Two cases of obsessive-compulsive disorder with depression responsive to trazodone.
    Author: Baxter LR.
    Journal: J Nerv Ment Dis; 1985 Jul; 173(7):432-3. PubMed ID: 4009160.
    Abstract:
    Two patients with severe obsessive-compulsive disorder with superimposed depression, who had failed to respond to a wide variety of antidepressants, were treated with trazodone hydrochloride. Both seemed to obtain a rapid and impressive improvement in both their depression and obsessive-compulsive disorder while receiving trazodone. One patient subsequently had a monoamine oxidase inhibitor added to his treatment and experienced some additional improvement, but most of his improvement had occurred earlier, while he was receiving trazodone only.
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