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  • Title: [Role of certain factors in thrombus formation in patients with myocardial infarct complicated by an acute aneurysm].
    Author: Charchoglian RA, Golikov AP, Levshunov SP.
    Journal: Ter Arkh; 1985; 57(4):81-6. PubMed ID: 4012638.
    Abstract:
    A total of 240 patients with acute myocardial infarction (MI) were examined over time with the use of two-dimensional echocardiography. The influence of such factors as the scope of involvement of the left ventricle myocardium, changes of its contractility and hemostasis on thrombus formation in the left ventricle was investigated. It was established that thrombus is formed primarily during anterior myocardial infarction with an extensive injury to the apical segment--formation of a large aneurysm. Thrombus formation is associated with a significantly large scope of the involvement and reduced (both total and segmental) left ventricle myocardial contractility, which may favour the development of hemostasis in the area of the aneurysm. It was discovered that two-dimensional echocardiography coupled with doppler cardiography is a highly sensitive technique, the use of which during MI enables recognizing patients predisposed to thrombus formation.
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