These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Formation of single-stranded regions in the course of digestion of DNA with DNAase II and micrococcal nuclease.
    Author: Galcheva-Gargova Z, Davidov V, Dessev G.
    Journal: Arch Biochem Biophys; 1985 Jul; 240(1):464-9. PubMed ID: 4015111.
    Abstract:
    In the course of digestion of DNA with DNAase II or micrococcal nuclease, considerable amounts of single-stranded (ss) regions are formed, as determined by a second digestion with ss-specific nucleases, hyperchromicity measurements, and electron microscopy. Most of the ss stretches are located internally in the DNA molecules. The effect appears to be related to regions of decreased stability arising around single-stranded cuts in the double helix.
    [Abstract] [Full Text] [Related] [New Search]