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  • Title: Toward a biochemical classification of depressive disorders IX. DST results and platelet MAO activity.
    Author: Schatzberg AF, Rothschild AJ, Gerson B, Lerbinger JE, Schildkraut JJ.
    Journal: Br J Psychiatry; 1985 Jun; 146():633-7. PubMed ID: 4016477.
    Abstract:
    Post-dexamethasone cortisol and platelet monoamine oxidase (MAO) activity levels were examined in 50 depressed patients. The incidence of non-suppression was significantly greater in patients with high platelet MAO activity than in those with low activity. Similar results were obtained when males and females were analysed separately. The mean 4 p.m. post-dexamethasone cortisol level was significantly higher in those patients who had high MAO activity than in their low MAO counterparts. Moreover, a statistically significant positive correlation was observed between platelet MAO activity and 4 p.m. post-dexamethasone cortisol levels.
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