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  • Title: Influence of secretagogues on volume and protein pattern in rabbit lacrimal fluid.
    Author: Stolze HH, Sommer HJ.
    Journal: Curr Eye Res; 1985 Apr; 4(4):489-92. PubMed ID: 4017638.
    Abstract:
    After certain tear proteins had been found to be markers of duct cell activity in the rabbit lacrimal gland, different secretagogues were tested to increase volume and protein secretion. Carbamyl-choline and the peptides eledoisin and vasoactive intestinal peptide (VIP) stimulated volume flux as well as secretion of the marker proteins indicating duct cell activation. Beta-adrenergic stimulation also increased secretion of a further tear protein. This might indicate that water is secreted by the duct cells. These are stimulated by the secretagogues mentioned above. Beta-adrenergic stimulation might in addition activate the acinar cell system.
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