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  • Title: Intracellular ionic changes during hyperthermia of tumor cells in the presence of lanthanum.
    Author: Anghileri LJ, Crône MC, Robert J.
    Journal: Neoplasma; 1985; 32(3):369-73. PubMed ID: 4022197.
    Abstract:
    The experimental data suggest that permeability changes at the plasma membrane level are the most likely cause of the enhancement of tumor cell killing by hyperthermia in the presence of 1 mM La3+. The interaction of La3+ with the Na+, K+ ATPase and Ca2+-pump ATPase may be the probable cause of dramatic electrolyte changes which enhance the hyperthermia effects on tumor cells.
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