These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The development of antioxidant enzymatic defense in the perinatal rat lung: activities of superoxide dismutase, glutathione peroxidase, and catalase.
    Author: Gerdin E, Tydén O, Eriksson UJ.
    Journal: Pediatr Res; 1985 Jul; 19(7):687-91. PubMed ID: 4022676.
    Abstract:
    This report describes the development of superoxide dismutase, glutathione peroxidase, and catalase activities in fetal (days 16-22) and neonatal (day 2 postpartum) lungs of normal rats. Each of the enzymes showed an individual pattern of development in the perinatal period. Glutathione peroxidase activity increased by 135% (p less than 0.001) during the last 3 days before birth, catalase activity by 105% (p less than 0.01) during the first 2 postnatal days, and the activity of superoxide dismutase by 52% (p less than 0.05) from gestational day 19 to 2 days after birth. Contamination by superoxide dismutase from blood in the lung samples accounted for less than 2% of the activity. In contrast, not less than 10-30% of glutathione peroxidase and catalase originated from the blood; and corrections were made for this source of error in each sample.
    [Abstract] [Full Text] [Related] [New Search]