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  • Title: Reversible coma in Wernicke's encephalopathy.
    Author: Gibb WR, Gorsuch AN, Lees AJ, Yudkin JS.
    Journal: Postgrad Med J; 1985 Jul; 61(717):607-10. PubMed ID: 4022893.
    Abstract:
    A case of coma due to Wernicke's encephalopathy complicated by respiratory failure is described. Ventilation and thiamine administration lead to recovery, although Korsakoff's psychosis and ataxia persisted. A review of similar cases of coma emphasizes the absence of diagnostic features, but that if structural disease is excluded the presence of pupillary and ocular signs may support a diagnosis of Wernicke's encephalopathy. The response to thiamine may be diagnostic as in 8 of these patients who received it, but the long-term morbidity remains high.
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