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  • Title: [Results of a double blind study with Segontin-Digoxin in coronary heart disease (author's transl)].
    Author: Nossen J.
    Journal: MMW Munch Med Wochenschr; 1977 Feb 04; 119(5):159-62. PubMed ID: 402569.
    Abstract:
    Segontin-Digoxin and digoxin were tested in a cross-over double blind trial in 30 patients with coronary heart disease and concomitant organic insufficiency in a cardiological specialist practice. As far as the coronary symptoms were concerned, treatment with Segontin-Digoxin was clearly superior to digoxin therapy alone. With regard to the elimination or improvement of signs of myocardial insufficiency, no difference could be established between the two preparations. A distinct lowering of heart rate and blood pressure, especially in hypertensives, was observed with Segontin-Digoxin therapy compared with digoxin alone.
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