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  • Title: Anti-acetylcholine receptor antibodies in myasthenia gravis. Part 3. The effect of thymectomy.
    Author: Oosterhuis HJ, Limburg PC, Hummel-Tappel E, Van den Burg W, The TH.
    Journal: J Neurol Sci; 1985 Jul; 69(3):335-43. PubMed ID: 4031948.
    Abstract:
    The clinical condition and the serum levels of antibodies to acetylcholine receptor protein were followed in 30 patients with myasthenia gravis before and in a period varying from 2 to 4 (mean 3) yr after thymectomy. Twenty-five patients improved in the 2 yr following thymectomy. A highly significant correlation was found between the change in clinical condition and the change in antibody levels. Only 3 patients improved without a fall of antibody level. Prethymectomy antibody levels were positively correlated with the severity of the clinical condition and with the degree of thymus hypertrophy.
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