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  • Title: Acid phosphatase activity of cerebrospinal fluid cells in leptomeningeal haemorrhage.
    Author: de Reuck J, de Coster W, Vander Eecken H.
    Journal: J Neurol; 1985; 232(3):154-6. PubMed ID: 4031958.
    Abstract:
    One hundred and twenty samples of haemorrhagic spinal fluid were examined by acid phosphatase staining. This enzyme activity starts to appear in mono-histiocytic cells 2 days after bleeding and increases up to the 5th day. After 1 week the activity decreases rapidly. Similar results are found in mixtures of incubated clear spinal fluid, to which blood is added. Acid phosphatase staining is a useful additional method for determination of the age of a leptomeningeal bleed.
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