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  • Title: A histologic study of epithelial dysplasia in oral lichen planus.
    Author: Odukoya O, Gallagher G, Shklar G.
    Journal: Arch Dermatol; 1985 Sep; 121(9):1132-6. PubMed ID: 4037838.
    Abstract:
    One hundred cases of oral lichen planus were reviewed together with 100 nonspecific oral mucosal inflammatory lesions as a control group. The presence of dysplasia was noted, using well-established histologic criteria. Mild dysplasia was found in 57% of cases, moderate dysplasia in 9%, and severe dysplasia in 2% of cases. In the control group, mild dysplasia was observed in 32% of cases, moderate in 10%, and severe dysplasia was not present. It is suggested that, while mild or moderate dysplasia may not indicate precancerous potential, severe dysplasia in lichen planus may signify the development of a precancerous lesion.
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