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  • Title: Lymphomatoid papulosis associated with plaque-stage and granulomatous mycosis fungoides.
    Author: Kardashian JL, Zackheim HS, Egbert BM.
    Journal: Arch Dermatol; 1985 Sep; 121(9):1175-80. PubMed ID: 4037844.
    Abstract:
    A 47-year-old black man had typical papulonodular lesions of lymphomatoid papulosis (LyP) with concurrent plaque-stage mycosis fungoides (MF). Both diagnoses were confirmed histologically. This supports the concept that LyP is part of the spectrum of cutaneous T-cell lymphoproliferative disorders. The patient also had a large nodule and a deeply infiltrated plaque, each of which exhibited a deep granulomatous reaction. These were interpreted as representing granulomatous MF. Clinically, there was an evolution from a predominance of LyP lesions to a predominance of MF plaques. Topical carmustine therapy resulted in a substantial decrease in the number and size of both LyP and MF lesions. Both lesion types involuted with hypopigmentation.
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