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  • Title: Tetrameric alkaline phosphatase in human liver plasma membranes.
    Author: Chakrabartty A, Stinson RA.
    Journal: Biochem Biophys Res Commun; 1985 Aug 30; 131(1):328-35. PubMed ID: 4038299.
    Abstract:
    Molecular weights of native membrane-bound alkaline phosphatase released by butanol and by nonionic detergents were more than twice that of the purified dimeric enzyme. Alkaline phosphatase released by phosphatidylinositol-specific phospholipase-C was of both high and low molecular weight: the former was a protomer of a single protein of the same molecular size as monomeric alkaline phosphatase. We conclude that the membrane-bound enzyme is probably a tetramer.
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