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  • Title: [Splenectomy for idiopathic thrombopenic purpura. A retrospective study of 40 cases].
    Author: Roy G, Fortin CL, Leblond PF.
    Journal: Can J Surg; 1985 Mar; 28(2):160-2. PubMed ID: 4038623.
    Abstract:
    The authors analysed retrospectively the files of 40 patients who underwent splenectomy for idiopathic thrombocytopenic purpura and who were totally or partially (relapse) resistant to a therapeutic trial of corticosteroids. There was no operative mortality but morbidity, especially respiratory, was substantial, being 40%. Drainage of the splenic bed should be avoided because this is clearly associated with a greater frequency of pulmonary complications. In 37 patients with a mean follow-up of 30.3 months, there was complete remission in 89.2% after splenectomy. This confirms the therapeutic value of splenectomy in idiopathic thrombocytopenic purpura, especially in those who showed a partial (transitory) response to corticosteroids.
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