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  • Title: The effects of soy flour and N-nitrosobis (2-oxopropyl) amine on the pancreas of the hamster.
    Author: Hasdai A, Liener IE.
    Journal: Drug Nutr Interact; 1985; 3(3):173-9. PubMed ID: 4040846.
    Abstract:
    Syrian golden hamsters fed diets of raw or heated soy flour for 16 months had an incidence (4%) of pancreatic neoplasms in both groups. Animals injected with N-nitrosobis (2-oxopropyl) amine (BOP) and fed heated soy flour for 15 months developed a high incidence (88%) of microscopic benign and malignant neoplasms, primarily of ductal origin. This was in marked contrast to a similar group of BOP-injected animals which had been fed raw soy flour and in which the incidence of pancreatic neoplasms was less than 10%.
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