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  • Title: [Role of antigen-binding cells in the formation of producers of antibodies and antigen-dependent nonspecific immunoglobulins].
    Author: Agadzhanian MG, Megrabian TB, Sidorova EV.
    Journal: Biull Eksp Biol Med; 1985 Sep; 100(9):327-9. PubMed ID: 4041601.
    Abstract:
    The role of antigen-binding cells in the formation of antigen-dependent nonspecific immunoglobulin producers in the Mishell-Dutton system was investigated. It was shown that the main part of antigen-dependent nonspecific immunoglobulin producers arise from the cells bearing antigen-specific receptors (as well as antibody producers). The nature of antigen-specific receptors of the precursors of antibody-forming and antigen-dependent nonspecific immunoglobulin-forming cells is discussed.
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