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  • Title: Clinical evaluation of some phosphorus bone-imaging agents: concise communication.
    Author: Nelson MF, Clifford McKee L, Van Wazer JR.
    Journal: J Nucl Med; 1977 Jun; 18(6):566-9. PubMed ID: 404405.
    Abstract:
    Four different Tc-99m labeled phosphorus-based bone-imaging agents were compared by a scan-evaluation technique in which the skeletal uptake was visually assessed at selected sites. A detailed statisticalanalysis of scans, by each of three independent evaluators, on a total of 140 different patients showed that two of the agents (based on pyro- and on trimetaphosphate) were superior. The statistical analysis showed good agreement between the investigators and consistency in thier repeat evaluations.
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