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  • Title: Concurrent pineoblastoma and unilateral retinoblastoma: a forme fruste of trilateral retinoblastoma?
    Author: Whittle IR, McClellan K, Martin FJ, Johnston IH.
    Journal: Neurosurgery; 1985 Sep; 17(3):500-5. PubMed ID: 4047365.
    Abstract:
    A 10-month-old boy who presented with strabismus and symptoms of intracranial hypertension was found to have a pineoblastoma and a unilateral ocular retinoblastoma. Despite enucleation of the eye, subtotal removal of the pineoblastoma, and craniospinal axis irradiation, the patient died 6 months later from disseminated intracranial neoplasm. As there was no clinical evidence of bilateral retinoblastoma, this case may represent a forme fruste of the trilateral retinoblastoma complex. The clinicopathological features of this unusual syndrome are reviewed.
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