These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effects of acute or chronic cadmium exposure on the adult mouse CNS: a freeze-fracture study.
    Author: Valois AA, Webster WS.
    Journal: Neurotoxicology; 1985; 6(3):37-43. PubMed ID: 4047514.
    Abstract:
    The effect of acute Cd exposure (0.5-12 mg CdCl2/kg body wt. for six hours) or chronic Cd exposure (40 ppm in the drinking water for 3 weeks) on the CNS of adult mice was investigated quantitatively by the use of the freeze-fracture technique to examine the nuclear membrane of cells from the cerebral cortex. Intramembrane particle density and nuclear pore density was determined for both the P face of the inner membrane and the E face of the outer membrane from control and experimental animals. The changes observed for both groups of experimental animals were similar in that particle numbers for both P and E faces were significantly increased over control values while nuclear pore numbers were unaffected. For the acute doses the increases were dose-dependent.
    [Abstract] [Full Text] [Related] [New Search]