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  • Title: [Geycogen content and the enzymatic system of its biosynthesis in normal and tumorous human tissues].
    Author: Mishemeva VS, Goriukhina TA, Burova TM, Kalinovskiĭ VP, Chekharina EA.
    Journal: Vopr Onkol; 1977; 23(2):79-82. PubMed ID: 404764.
    Abstract:
    In human tumors (cancer of the liver, stomach, lymphogranulomatosis of lymphnodes, metastases in lymphnodes, ascites ovarian tumor cells) the authors studied the content of enzymes participating in glycogen biosynthesis through uridine diphosphateglucose mechanism--UDPG-glycogensynthetase, UDPG-pyrophosphroylase, phosphoglucomutase. As a rule, in human tumor cells the amount of glycogen and the activity of enzymes of its biosynthesis is decreased, the more the higher proliferative activity and autonomization of tumor cells.
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