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  • Title: Frequency of IgA deficiency in blood donors and Rh negative women in Iceland.
    Author: Gudmundsson S, Jensson O.
    Journal: Acta Pathol Microbiol Scand C; 1977 Apr; 85(2):87-9. PubMed ID: 404845.
    Abstract:
    Sera from 6,842 individuals were tested for IgA deficiency, using double and radial immunodiffusion. Sera containing less than 1 mg/100 ml of IgA were classified as deficient. The frequency of selective IgA deficiency among 4,799 blood donors investigated was 1:533, but 1:340 among 1,017 Rh negative women screened and 1:485 for both groups combined. One of the nine IgA deficient blood donors detected belonged to a 1st cousin marriage family previously investigated, in which the mother also was deficient in IgA. One IgA deficient recipient was found among 704 hospital patients screened for this abnormality.
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