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  • Title: Cold reacting antibodies recognizing antigens dependent on N-acetylneuraminic acid.
    Author: Staub CA.
    Journal: Transfusion; 1985; 25(5):414-6. PubMed ID: 4049485.
    Abstract:
    Serum from a 75-year-old man with lymphoproliferative disease was found to contain a persistent cold agglutinin meeting most of the characteristics of examples of anti-Gd reported previously. It differed, however, in that it contained IgG and IgM components and its reactivity was not inhibited by sialyllactose. A search of random serums containing cold agglutinins was undertaken to determine the incidence of antibodies to antigens dependent on N-acetylneuraminic acid. Two further examples were found in 47 serums containing cold agglutinins. One of these also demonstrated a Gd or "Gd-like" specificity. The other appeared to be an anti-Pr.
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