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  • Title: The validity of neurotic-reactive depression. New data and reappraisal.
    Author: Winokur G.
    Journal: Arch Gen Psychiatry; 1985 Nov; 42(11):1116-22. PubMed ID: 4051688.
    Abstract:
    A family history of alcoholism can be used as a validating factor in the diagnosis of reactive-neurotic depression. Not only is this true but there are clear data that indicate the presence of positive symptoms that can be used to make the diagnosis. A set of criteria based on previous research is presented for the diagnosis of neurotic-reactive depression. These criteria are based on a clustering of certain symptoms, events, and traits in patients with neurotic-reactive depression. The patients showed stormy life-styles, some specific symptoms, personality abnormalities, presence of life events before the onset of depression, and a family history of alcoholism. They had relatively few hospitalizations for depression and responded poorly to specific antidepressant treatment.
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