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  • Title: [Changes in the adrenal medulla of the rat during immobilization stress].
    Author: Shvalev VN, Kargina-Terent'eva RA, Mar'ian KL, Pavlovich ER.
    Journal: Arkh Anat Gistol Embriol; 1985 Aug; 89(8):97-102. PubMed ID: 4051796.
    Abstract:
    A combined histofluorescent, light optic and electron microscopic investigation has been performed to study the medulla of the adrenals in intact rats (August strain) and immediately after immobilization for 30 h and 24 h after. In the intact animals heteromorphism of the medulla is demonstrated; this depends on the fact that adrenocytes are at different stages of the secretory cycle. Immobilization for 30 h results in synchronization of secretion; this is determined by adaptation of the adrenal system to immobilization. One day after immobilization restoration of heteromorphism in chromaffinocytes is demonstrated. The changes described are compensatory-adaptive reactions of the adrenal medulla to the stress in the animals survived.
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