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  • Title: [Development of multicentric invasive cancer of the esophagus against a background of epithelial dysplasia and preinvasive cancer].
    Author: Frank GA, Mamontov AS, Sokolova NV.
    Journal: Arkh Patol; 1985; 47(7):55-7. PubMed ID: 4051816.
    Abstract:
    Two observations of squamous cell carcinoma of the oesophagus developing in the presence of multiple confluent areas of dysplasia (degree II and III) and multiple foci of preinvasive carcinoma are described. The authors claim that their observations confirm the concept of a tumourous field on the basis of which dysplastic changes and neoplastic growth develop.
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