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  • Title: [Prognostic value of determining the succinate dehydrogenase activity of lymphocytes and the therapeutic effectiveness of sodium succinate in resuscitation of rats].
    Author: Baranets NA, Dolgikh VT, Nartsissov RP.
    Journal: Biull Eksp Biol Med; 1985 Oct; 100(10):405-7. PubMed ID: 4052601.
    Abstract:
    In the experiments on male rats recovered after clinical death caused by acute hemorrhage and mechanical asphyxia undulatory changes of lymphocyte succinate dehydrogenase activity were revealed: enzyme inhibition during clinical death, activation in the first minutes of resuscitation with subsequent moderate reduction in activity. Lymphocyte succinate dehydrogenase activity was shown to be a reliable prognostic criterion. Pre-injection of sodium succinate at a dose of 20 mg/kg improved considerably the resuscitation results especially during the first two days of rehabilitation period.
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