These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Prolonged toxicity following massive ingestion of sustained-release theophylline preparation.
    Author: Corser BC, Youngs C, Baughman RP.
    Journal: Chest; 1985 Nov; 88(5):749-50. PubMed ID: 4053717.
    Abstract:
    Massive ingestion of sustained-release theophylline preparations in three patients was treated with gastric lavage and repeated dosages of orally-administered activated charcoal. Therapy was initiated promptly; however, two patients had their highest theophylline levels documented six to 12 hours after ingestion, and theophylline levels on arrival at the hospital were significantly lower than the maximal level documented. All three patients had prolonged elevations of the level, with markedly delayed half-lives of the drug. Overdosages due to sustained release preparations may lead to prolonged toxicity and require aggressive and continuous therapy.
    [Abstract] [Full Text] [Related] [New Search]