These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Hydration stability of intracorneal hydrogel implants.
    Author: Beekhuis WH, McCarey BE.
    Journal: Invest Ophthalmol Vis Sci; 1985 Nov; 26(11):1634-6. PubMed ID: 4055296.
    Abstract:
    A hydrogel intracorneal lens for refractive keratoplasty must have predictable and stable optics when implanted in the corneal stroma. A series of experiments was performed to evaluate the hydrogel hydration stability when in the corneal stromal environment. Hydrogel ICLs of 54%, 63%, 66% and 71% water content showed no loss of hydration (by weight) after one week in the rabbit corneal stroma. In vitro experiments with hydrogel discs of 56%, 65%, 69.5% and 75% water content were subjected to swelling pressures ranging from 55 to 150 mmHg in a suction chamber. Only the hydrogel of 75% water content showed a significant loss of hydration at the physiologic swelling pressure of 55 mmHg. This study shows that hydrogel materials with up to 69.5% water content can be expected to be dimensionally stable when used in keratorefractive surgery.
    [Abstract] [Full Text] [Related] [New Search]