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  • Title: Microinvasive carcinoma of the vagina: a distinct clinical entity?
    Author: Peters WA, Kumar NB, Morley GW.
    Journal: Am J Obstet Gynecol; 1985 Nov 01; 153(5):505-7. PubMed ID: 4061511.
    Abstract:
    Six patients with superficially invasive squamous carcinoma of the vagina are described. All had less than 2.5 mm of invasion as measured from the surface, lacked involvement of the lymph-vascular spaces, and arose within a field of carcinoma in situ. Three of the six had previously been treated for carcinoma of the cervix. The patients with microinvasive carcinoma had a median age 10 years younger than that of patients with Stage I carcinoma of the vagina. Treatment of the six patients has been by partial or total vaginectomy. With follow-up of 51 to 172 months, there have been no recurrences. More experience is needed to define microinvasive squamous carcinoma of the vagina and to determine the optimal treatment for these lesions.
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