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  • Title: [Effect of immunostimulants on kidney tubule secretion of xenobiotics].
    Author: Berkhin EB.
    Journal: Biull Eksp Biol Med; 1985 Nov; 100(11):584-6. PubMed ID: 4063508.
    Abstract:
    Excretion of cardiotrast (diotrast) was used to study tubular secretion of organic compounds in rats. Immunostimulants prodigiosin (0.05 mg/kg) and levamisole (10 mg/kg) injected subcutaneously three times every other day increased cardiotrast excretion. High levamisole dose (50 mg/kg), having no stimulating effect on the immunity, failed also to influence tubular cardiotrast transport. Possible mechanisms of immunostimulants' action on the tubular secretion of xenobiotics is discussed.
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