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  • Title: [Comparative analysis of the malignancy of tumors in mice induced by 20-methylcholanthrene].
    Author: Viksler VKh, Iaroslavtseva OA, Lavroskiĭ VA.
    Journal: Eksp Onkol; 1985; 7(5):21-4. PubMed ID: 4065015.
    Abstract:
    Malignancy of 13 cell cultures cultivated in vitro was studied. 11 cultures were induced by subcutaneous injection of 20-methylcholanthrene to 3 lines of mice. The malignancy was studied by transplantability, growth rate and metastasis formation after subcutaneous injection of a various cell number into normal and sublethally irradiated syngenic mice. A convenient model for studying the significance of certain immunological properties of tumour cells in determination of the malignancy was obtained.
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