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  • Title: [The therapeutic effects of aspoxicillin on various infectious diseases in children].
    Author: Wakiguchi H, Maeda A, Ohara Y, Tone Y, Araki K, Shiraishi T, Ogura H, Kitamura I.
    Journal: Jpn J Antibiot; 1985 Jul; 38(7):1925-30. PubMed ID: 4068226.
    Abstract:
    Clinical application to ascertain the effects of aspoxicillin (ASPC), a new semisynthetic penicillin antibiotic, upon several infectious diseases of children was performed in 7 cases with pneumonia, 5 cases with acute bronchitis, each case with tonsillitis, enterocolitis, urinary tract infection and suspected sepsis. ASPC was injected by drip infusion and the dosage was 63-117 mg/kg/day in 3 and 4 times a day. Clinical efficacy obtained as "excellent" was in 7 cases, "good" in 8 cases "poor" in 1 case, and efficacy rate was 93.8%. From the bacteriological point of view, eliminated in each of H. influenzae, H. parainfluenzae, group A beta-Streptococcus and unchanged in a case of E. coli. There were transient thrombocytopenia in 2 cases and eosinophilia in 3 cases.
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