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  • Title: [Features of the formation of the cortical "kindling" phenomenon in acute experiments on cats].
    Author: Okudzhava VM, Goff VG, Zolotilina EG.
    Journal: Neirofiziologiia; 1985; 17(5):601-6. PubMed ID: 4069277.
    Abstract:
    The possibility of cortical "kindling" organization in short time interval (2-3 hours) was shown in acute experiment on cats. The middle area of g. suprasilvius was stimulated by square current pulses (20 per s, 1 ms duration for 5 s with interstimulus intervals of 3 min). As a result of stimulation after the projection discharge in the mirror focus the convulsive activity generalization and formation of independent secondary focuses were observed. In the process of formation of cortical "kindling" the activity of spindle waves could be recorded in all ECoG traces. The frequency of spindle emergence grew according to the epileptization of the animal. The spindle activity transformation into the multiple spike-wave activity was also recorded. The results obtained proved the participation of subcortical structures in the formation of cortical "kindling".
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