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Title: Abnormally low UV-induced unscheduled DNA synthesis in cells from a patient with hydroa vacciniforme. Author: Andrews AD, Halasz CL, Poh-Fitzpatrick MB. Journal: Photodermatol; 1985 Oct; 2(5):315-8. PubMed ID: 4070030. Abstract: Skin fibroblasts from a patient with the photosensitive disorder hydroa vacciniforme were tested in vitro for DNA repair capacity. The rate of ultraviolet light (254 nm)-induced unscheduled DNA synthesis (UDS) in these fibroblasts was found to be 51-59% of the rate found in 4 normal fibroblasts strains. The patient had none of the clinical signs of the classic DNA deficient disease, xeroderma pigmentosum.[Abstract] [Full Text] [Related] [New Search]