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  • Title: [Changes in serum lipid levels and the spectrum of individual fatty acids in patients with chronic renal failure on conservative and hemodialysis treatment and their relation to dietary protein intake].
    Author: Orbetsova V, Simeonov P, Todorov K, Elazarova F.
    Journal: Vutr Boles; 1985; 24(4):63-70. PubMed ID: 4072171.
    Abstract:
    The serum lipids level, lipoproteins with very low and low density and individual fatty acids were studied in three groups of patients with chronic renal insufficiency (ChRI) on conservative treatment, on hemodialysis to 12 months and over 12 months, looking for a connection with the ChRI stage, with the effect of hemodialysis and diet. A tendency to decrease of the levels of beta-lipoproteins (beta LP) and total cholesterol (TCh) in beta LP was outlined from conservative to hemodialysis ChRI, hyperprebeta--lipoproteinemia, with S-fraction being established more often. That explains the great discrepancies in lipoprotein--profile among the three groups of patients, the dietetic factor, likely to play a decisive role for that. For the same reasons, deficiency of essentail fatty acids--linoleic and arachidonic was esotablished in the patients with conservative ChRI, eliminated in the course of dialysis. Since serum albumins show a substantial correlative relationship with palmiatic, stearic, linoleic, acid, beta LP and TCh in beta LP, those lipid indices could be admitted to follow the protein-caloric deficiency in the patients with ChRI, in the conservative therapeutic stage in particular. Those data necessitate a critical antitude to the strict hypoprotein regimen in them.
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