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  • Title: [Clinical dynamics of cenesto-hypochondriacal neurosis-like disorders in schizophrenia with onset in adolescence (clinico-catamnestic study)].
    Author: Matveev VF, Kochergina IuV, Prokudin VN.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1985; 85(10):1545-9. PubMed ID: 4072518.
    Abstract:
    For 10-15 years the authors studied the time-course of neurosis-like disturbances in 46 patients with schizophrenia manifested in adolescence with cenesthopathic symptomatology (23 patients presented the cenesthopathic-hypochondriac syndrome, in 17 cenesthopathia was attended by phobias, in 6 it was combined with manifestations of derealization and depersonalization). The study showed that in 87% of the observations the disease ran continuously (torpidly in 29, by the type of the simple form in 5 and by the type of the paranoid form in 6 patients), in 13% of the patients the disease ran a paroxysm-progressive course. In 10-15 years the clinical picture in half of the patients continued to be characterized by the leading cenestho-hypochondriac symptomatology, in one-fourth of patients cenestho-hypochondriac disturbances were transformed into hallucinational-paranoid, in another one-fourth of patients into either psychosis-like or apathoabulic (by the type of the simple form) symptomatology. The authors discuss the degree of progression of the disease in different variants of its course, the social and marital status of patients, the specificity of personality changes and peculiarities of disease relapses.
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