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  • Title: [Common variable hypogammaglobulinemia. Apropos of a new case].
    Author: Laurent P, Girod B, Dutertre R.
    Journal: Arch Fr Pediatr; 1985 Oct; 42(8):701-3. PubMed ID: 4074099.
    Abstract:
    The authors report the case of a 17 year-old girl who presented with typical clinical features (pneumonia, sinusitis, otitis and diarrhoea) of Variable Primary Hypogammaglobulinemia for over 15 years. Immunodeficiency investigations showed a defective antibody response with a panhypogammaglobulinemia but normal cell-mediated immunity. Serum protein electrophoresis and detection of natural and acquired antibodies in the blood are the basic biological tests to run for a quick diagnosis. The main long term complication consists of the risk of neoplasia. The patient recovered a good clinical status after she was treated by IgG infusions every 2,5 weeks and antibiotics in case of superimposed infection.
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