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  • Title: Defective interferon-alpha production in children with recurrent respiratory tract infections. A primary or secondary deficiency?
    Author: Pugliese A, Salomone C, Martino S, Biglino A, Delpiano A, Tovo PA.
    Journal: Boll Ist Sieroter Milan; 1985; 64(4):328-31. PubMed ID: 4074516.
    Abstract:
    Interferon-alpha and -gamma production was assayed in 44 children with recurrent respiratory tract infections, in 9 patients with recurrent stomatitis and in 32 control subjects. A partial, transitory deficiency in interferon-alpha production was found in 2 children with recurrent respiratory tract infections. The deficiency may be either cause or effect of the recurrent infections. Many data support the latter hypothesis.
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