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  • Title: Electron microscopic study on the innervation of the human lower respiratory tract: evidence of adrenergic nerves.
    Author: Laitinen A, Partanen M, Hervonen A, Laitinen LA.
    Journal: Eur J Respir Dis; 1985 Sep; 67(3):209-15. PubMed ID: 4076358.
    Abstract:
    Samples of human lung were studied electron microscopically after fixation with glutaraldehyde and osmium tetroxide. Three different types of nerve profiles were found in the human lower respiratory tract. Type I nerve profiles contained small agranular vesicles 30-50 nm and large granular vesicles ranging from 60 nm to 210 nm. Type II nerve profiles contained small granular vesicles 30-50 nm and a few large granular vesicles ranging from 60 to 120 nm. Type III nerve profiles contained predominantly large irregular vesicles ranging from 60 to 210 nm, and only a few small agranular vesicles. The present electron microscopic results indicate that the smooth muscle layer of human bronchial tree receives adrenergic nerves.
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