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  • Title: Synthesis and some biological properties of new derivatives of 1-S-phenylthioglycolonitrile.
    Author: Makosza M, Ludwikow M, Ernest K, Bogdal M, Przemyk B, Filczewski M, Oledzka K.
    Journal: Pol J Pharmacol Pharm; 1985; 37(4):551-63. PubMed ID: 4080649.
    Abstract:
    A series of new S-phenylthioglycolic acid derivatives was synthetized via common transformations of alkylated S-phenyl-thioglycolonitrile. The compounds were submitted to pharmacological screening. N,N-Diethylaminoethyl ester of 1-S-phenylcyclopentane carboxylic acid was submitted to detailed studies and showed high local anesthetic properties.
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