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  • Title: [2-14C-phenazepam metabolism in vitro].
    Author: Golovenko NIa, Zin'kovskiĭ VG.
    Journal: Farmakol Toksikol; 1979; 42(6):597-600. PubMed ID: 40817.
    Abstract:
    Phenazepam undergoes aromatic and C3-hydroxylation in the microsomes of albino rats. Saturation of phenazepam oxidising enzymes proceeds at different substrate concentrations for both processes. Interaction of cytochrome P-450 with phenazepam is accompanied by spectral changes in the type II hemoprotein.
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