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Title: Assignment of the mouse alpha A-crystallin structural gene to chromosome 17. Author: Kaye NW, Church RL, Piatigorsky J, Petrash JM, Lalley PA. Journal: Curr Eye Res; 1985 Dec; 4(12):1263-8. PubMed ID: 4085253. Abstract: alpha A2-crystallin is one of the major water-soluble proteins of the mammalian lens. Using a cloned cDNA probe coding for mouse alpha A2-crystallin and Southern blot hybridization, DNA isolated from a panel of somatic cell hybrids prepared from mouse fibroblasts or mouse spleen cells fused with Chinese hamster fibroblasts was probed to determine the chromosomal localization of the alpha A2-crystallin structural gene. We have located this gene on mouse chromosome 17.[Abstract] [Full Text] [Related] [New Search]