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  • Title: Synthesis of some isonicotinoyl- and nicotinoyl-sulphonylamino acid derivatives and their antimicrobial activity.
    Author: el-Naggar AM, Sammour AA, Kora FA, el-Nemma EM.
    Journal: Farmaco Sci; 1985 Oct; 40(10):786-94. PubMed ID: 4085642.
    Abstract:
    The synthesis of isonicotinoylamino acids-2-sulphonylamino acids and nicotinoylamino acids-5-sulphonylamino acids (III-VII) and (XXIII-XXVII) and their corresponding methyl esters, hydrazides and some dipeptide methyl ester derivatives (VII-XXII) and (XXVIII-XXXVII) are described. Thirty two of various substituted nicotinoyl and isonicotinoyl sulphonylamino acid derivatives were found to possess specific antimicrobial activities towards different microorganisms.
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