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  • Title: [Synthesis and pharmacologic study of 6-(amino-2 ethyl) benzoxazolinones].
    Author: Caignard DH, Couquelet J, Lesieur D, Lespagnol C, Lamar JC, Beaughard M, Leinot M, Tisne-Versailles J.
    Journal: Farmaco Sci; 1985 Nov; 40(11):854-68. PubMed ID: 4085645.
    Abstract:
    Reaction of various amines on 6-(2-bromoethyl)benzoxazolinone or its N-methylated derivative provided eleven new 6-substituted aminoalkyl analogues. In a pharmacological evaluation, several compounds bearing an arylpiperazinic moiety were found to possess significant effects on arterial blood pressure and on the central nervous system; two of them showed interesting analgesic activity.
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