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  • Title: [Synthesis and analgesic activity of 3-substituted derivatives of pyrido [3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-ones].
    Author: Bousquet E, Romeo G, Guerrera F, Caruso A, Amico-Roxas M.
    Journal: Farmaco Sci; 1985 Nov; 40(11):869-74. PubMed ID: 4085646.
    Abstract:
    A series of Schiff bases of 3-amino-2,7,9-trimethylpyrido-[3',2',:4,5]thieno[3,2-d]pyrimidin- 4(3H)-one with aromatic aldehydes was synthesized. The compounds showed interesting analgesic activity without effects on the stomach even with oral doses of 200 mg/kg.
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