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  • Title: [Rate of blood flow in the microvessels of the brain of the rat with spontaneous arterial hypertension].
    Author: Kisliakov IuIa, Levkovich IuI, Volodina IL.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1985 Nov; 71(11):1355-61. PubMed ID: 4085649.
    Abstract:
    In normal and hypertensive rats, hematological indices were studied as well as the linear blood flow velocity in the microvessels with diameter 6-12 mu. Both groups of animals were shown to develop obvious oscillations of the blood velocity coinciding neither with heart beats nor with respiratory movements. In rats with spontaneous arterial hypertension, the mean velocity was 844 mu/sec and the amplitude of blood flow oscillations was 175 mu/sec which was higher by 35% and 33.5% resp. than in control animals. The erythrocyte concentration, hematocrit value and the amount of hemoglobin were higher by 11, 26 and 20% resp. in hypertensive animals. The revealed differences of the blood flow in hypertensive rats are due to the increased blood pressure, specific architectonics of the vascular bed and to changes of the blood rheological features.
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