These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Micellar effects on the basic hydrolysis of indomethacin and related compounds.
    Author: Cipiciani A, Ebert C, Germani R, Linda P, Lovrecich M, Rubessa F, Savelli G.
    Journal: J Pharm Sci; 1985 Nov; 74(11):1184-7. PubMed ID: 4087178.
    Abstract:
    The kinetics of hydrolysis of indomethacin and related compounds was studied in an alkaline medium at 25 degrees C in the presence of anionic (sodium dodecyl sulfate) and cationic (hexadecyltrimethylammonium bromide) surfactants. The rate-surfactant profiles for rate inhibition in the presence of sodium dodecyl sulfate and rate enhancement in the presence of hexadecyltrimethylammonium bromide were analyzed in terms of the current theory of micellar effects.
    [Abstract] [Full Text] [Related] [New Search]