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Title: Purine acyclic nucleosides. 6-Dimethylamino-9-[(2-phenylalanylamido-1-substituted- ethoxy)methyl]purines as candidate antivirals. Author: Kelley JL, Selway JW, Schaeffer HJ. Journal: J Pharm Sci; 1985 Dec; 74(12):1302-4. PubMed ID: 4087197. Abstract: Several acyclic puromycin analogues containing hydrocarbon substituents on the 1'-position of the aminoethoxymethyl moiety were synthesized and tested for antiviral activity. The N-carbobenzoxy intermediate 7c was active in vitro against Mengo and Semliki Forest viruses.[Abstract] [Full Text] [Related] [New Search]